WebThe molecular interactions of fibroblast growth factor 23 (FGF23), klotho and vitamin D coordinate to regulate the delicate phosphate levels of the body. Vitamin D can induce … WebThe present study was carried out to evaluate the effect of dietary supplemental vitamin D_(3) on fibroblast growth factor 23(FGF23)signals as well as phosphorus homeostasis and metabolism in laying hens.Fourteen 40-week-old Hy-Line Brown layers were randomly assigned into 2 treatments:1)vitamin D_(3) restriction group(n=7)fed 0 IU/kg vitamin D ...
Klotho: An antiaging protein involved in mineral and vitamin D ...
WebBy suppressing the synthesis of active vitamin D and promoting the formation of inactive vitamin D, FGF23 lowers the serum levels of active vitamin D. The parathyroid gland is … WebApr 15, 2024 · The Klotho gene (also known as α-Klotho) is located on chromosome 13q12 and it was first identified as an anti-aging factor 33. It is expressed in the kidney and even less in the pancreatic ... lm wheels
FGF23, klotho and vitamin D interactions: What have we learned ...
Web1,25-dihydroxyvitamin D (1,25D), through association with the nuclear vitamin D receptor (VDR), exerts control over a novel endocrine axis consisting of the bone-derived hormone … WebVitamin D and parathyroid hormone (PTH) that play particular functions in calcium and phosphate homeostasis may be involved in the etiology of this disorder. Klotho, the co-receptor of the fibroblast growth factor 23 (FGF-23), can interfere with calcium and phosphate metabolism. WebDec 21, 2024 · In chronic kidney disease (CKD) (red dotted line), there is a reduction in Klotho expression, alongside a decrease in Vitamin D levels and an increase in fibroblast growth factor (FGF-)23 levels. It is important to mention that the decrease of Vitamin D is related to the decrease of Klotho in the kidneys, which then leads to a rise in FGF-23 ... india gate hd wallpaper download