WebA stable, microcrystalline form of cisplatin, a process for its preparation, and stable, sterile dry-mix formulations thereof which are more rapidly reconstituted with sterile water to produce... WebCisplatin is a platinum chemotherapeutic used in a variety of malignancies. The antineoplastic activity occurs from DNA cross-links and adducts, in addition to the generation of superoxide radicals. Nephrotoxicity is the most well-known and potentially most clinically significant toxicity. Unfortunately, the mechanism for cisplatin ...
azane;dichloroplatinum Cl2H6N2Pt - PubChem
WebJun 15, 2024 · Keywords: 3-MethylAdenine (3-MA) (PubChem CID: 1673); 5-Fluorouracil (5-FU) (PubChem CID: 3385); Allicin (PubChem CID: 65036); Apatinib (PubChem CID: 45139106); Arsenic trioxide (As (2)O (3)) (PubChem CID: 14888); Autophagy; Bafilomycin A1 (PubChem CID: 6436223); Bortezomib (PubChem CID: 387447); Brefeldin A … WebPurpose: Cisplatin resistance is a major concern in ovarian cancer treatment. The aim of this study was to investigate if wedelolactone could perform better in resistant ovarian cancer cells when used in combination with cisplatin. Methods: Growth inhibitory potential of wedelolactone and cisplatin was investigated through MTT reduction assay ... binkyart.com
Cisplatin Pharmaceutical Secondary Standard; Certified Reference ...
WebC2210000 Cisplatin European Pharmacopoeia (EP) Reference Standard Synonym (s): cis-Diammineplatinum (II) dichloride, cis-Dichlorodiammine platinum (II), cis-Platinum (II) diammine dichloride, Cisplatin Linear Formula: Pt (NH3)2Cl2 CAS Number: 15663-27-1 Molecular Weight: 300.05 EC Number: 239-733-8 MDL number: MFCD00011623 … WebCisplatin is an antineoplastic agent that is FDA approved for the treatment of metastatic testicular tumors, metastatic ovarian tumors, and advanced bladder cancer. There is a Black Box Warning for this drug as shown here. Common adverse reactions include anemia, leukopenia, and thrombocytopenia . Adult Indications and Dosage WebChemical Name. cis-Diaminodichloroplatinum. Biological Activity. Potent anticancer agent that blocks DNA synthesis. Induces apoptosis via p53-dependent and -independent mechanisms. Inhibits X-linked inhibitor of apoptosis protein (XIAP) expression and activates caspase-3. In certain glioma cell lines, sensitizes cells to TNF-α-induced apoptosis. binkw32 dll download for pc